BREATHE SURE

SKU: FP-BS-001

Rs. 845.00
Quantity:
60 Vegetarian capsules
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Manage respiratory disorders with an effective long-term solution Breathe Sure is a powerful natural solution for the effective regulation of respiratory disorders and infections. It contains the well-researched botanical Boswelliaserrata, widely studied for its anti-oxidant...
Benefits
  • Pure Boswellia serrata extract works as a long-term solution in the management of respiratory tract disorder
  • Reduces tightness in the chest and breathlessness
  • Helps control coughing and wheezing at night/early morning
  • Reduces mucous secretion and therefore helps address infections such as bronchitis and sinusitis
  • Improves overall lung capacity and volume

Manage respiratory disorders with an effective long-term solution

Breathe Sure is a powerful natural solution for the effective regulation of respiratory disorders and infections. It contains the well-researched botanical Boswelliaserrata, widely studied for its anti-oxidant and anti-inflammatory properties. The exceptional efficacy of Breathe Sure can be attributed to theBoswellia extract that it contains, standardized to the powerful bioactive ingredient AKBA (acetyl ketoboswellic acid).

Studies have proved that AKBA has the unique ability to inhibit both 5LOX (5 lipoxygenase) and HLE (human leukocyte elastase), that are the biomolecules responsible for bronchial muscle contraction and mucous secretion respectively. By this mechanism, Breathe Sure helps relieve breathlessness, tightness of the chest, coughing and wheezing, and is therefore effective in the management of respiratory tract disorders and infections. The dual inhibition of 5-LO and HLE is unique to boswellic acids. AKBA alone is not sufficientto get the full benefits of boswellia: the synergism between AKBA and other acetyl group of BA in boswellia gives it its superior anti- inflammatory activity. 

Mechanism of action

The key active ingredient of the boswelliaserrata extract are the boswellic acids (BA). Of the various acids, the acetyl group of BA is the most potent anti- inflammatory agents. and the most active acetyl BA is Acetyl ketoboswellic acid (AKBA). Breathe Sure is standardised with acetyl group of BA with 10% AKBA.

Boswellic acids are specific, non-reducing type inhibitors of 5-lipoxygenase (5-LO), one of the two key enzymes in arachidonic acid metabolism and eicosanoid synthesis leading to inflammation. 5-LO catalyzes the first two steps in the biosynthesis of leukotrienes (LTs) from arachidonic acid to 5-hydroperoxyeicosatetraenoic acid (5(S)-HETE) and subsequently to LTA4, which is further converted to LTB4. LT cause broncho-constriction and mucus secretion and induce plasma exudation, that plays an important role in asthma.

BA also inhibits human leukocyte elastase (HLE) which stimulates mucus secretion and thus may play a role in cystic fibrosis, chronic bronchitis and acute respiratory distress syndrome. HLE initiates injury to the tissues triggering the inflammatory process.

The key active ingredient of the boswellia serrata extract are the boswellic acids (BA). Of the various acids, the acetyl group of BA is the most potent anti- inflammatory agents. and the most active acetyl BA is Acetyl keto boswellic acid (AKBA). Breathe Sure is standardised with acetyl group of BA with 10% AKBA. Boswellic acids are specific, non-reducing type inhibitors of 5-lipoxygenase (5-LO), one of the two key enzymes in arachidonic acid metabolism and eicosanoid synthesis leading to inflammation. 5-LO catalyzes the first two steps in the biosynthesis of leukotrienes (LTs) from arachidonic acid to 5-hydroperoxyeicosatetraenoic acid (5(S)-HETE) and subsequently to LTA4, which is further converted to LTB4. LT cause broncho-constriction and mucus secretion and induce plasma exudation, that plays an important role in asthma. • BA also inhibits human leukocyte elastase (HLE) which stimulates mucus secretion and thus may play a role in cystic fibrosis, chronic bronchitis and acute respiratory distress syndrome. HLE initiates injury to the tissues triggering the inflammatory process. • The dual inhibition of 5-LO and HLE is unique to BA.
Serving size:
250 Mg capsules containing Carbohydrate: 10 mg, Protein: 4.3 mg, Fat : 13.8 mg, Energy Value (Kcal/ capsule) 0.2:

Recommended usage:
1-2 Capsules in the morning and at night after food.

Net content:
60 Vegetarian Capsules.

Directions:
Store in a cool and dry place. If pregnant or under medication, consult your health care practitioner before using. Keep out of reach of children.

Boswellic Acids in Chronic Inflammatory Diseases

Ammon HP.

Publication: Planta Medica

https://www.thieme-connect.com/products/ejournals/html/10.1055/s-2006-947227

Oleogum resins from Boswellia species are used in traditional medicine in India and African countries for the treatment of a variety of diseases. Boswellic acids present in Boswellia are responsible for many of its pharmacological effects. Boswellia serrata is useful in treating bronchial asthma. There are differences between the anti-inflammatory actions of Boswellic acid and aspirin-like drugs.

Boswellia extract is useful in controlling many chronic diseases that are related to autoimmune disorders. These include rheumatic diseases, inflammatory bowel diseases, bronchial asthma and others.

A-90 Day Gavage Safety Assessment of Boswellia serrata in Rats

Pooja Singh, K. Mathai Chacko, M. L. Aggarwal, Binu Bhat, R. K. Khandal, Sarwat Sultana1, Binu T. Kuruvilla

Publication: Toxicology International

http://www.toxicologyinternational.com/temp/STOX193273-8352542_231205.pdf

The in-depth study conducted by the authors deals with the evaluation and assessment of the toxicity of Boswellia serrata, a well-known Ayurvedic herb used to treat disorders of digestive system, respiratory ailments and bone related diseases. The results of the study indicate that Boswellia serrata is relatively safe in rat up to a dose of 500 mg/kg of body weight as no adverse effects on health factors were observed.

Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis

Reji  Kizhakkedath

Publication:  Molecular Medicine reports

http://www.spandidos-publications.com/mmr/8/5/1542

Osteoarthritis is physically debilitating and significantly impairs quality of life. As the cause of it remains unknown, current medical treatment is directed towards alleviating pain and restoring movement using nonsteroidal anti-inflammatory drugs (NSAIDs).

The Boswellia extract used in this study was "enhanced" to contain 10% AKBA and curcumin was bioactive curcumin   through BCM95.

The authors conclude that improvements in pain severity, walking distance, and joint tenderness were superior in those taking the curcumin - Boswilla supplement compared to the NSAID control medication.

1. What are the common indications that can be managed with Boswellia Extract?

  1. Osteoarthritis (OA)
  2. Rheumatoid Arthritis (RA)
  3. Asthma
  4. Inflammatory Bowel Disease

    2. Are there any side effects if and when used for long time?

    Studies have shown that Boswellia extract does not have any side effects.

    3. What are NSAIDs and why a combination of Boswellia -Curcumin extract is superior to it?

    NSAIDs are non- steroid anti-inflammatory drugs, a common drug used in the treatment of knee pain (Osteoarthrities). In some case NSAIDs may affect gastrointestinal, renal, and cardiovascular systems. Boswillia - Curcumin (10% AKBA and Bio available Curcumin) combination is highly effective in managing OA and various studies have shown that it does not affect any other physiological systems.

    4. Is Boswillia –Curcumin combination available easily in the market?

    It is not available over the counter. Orders can be made through the website www.curegarden.in