The Curegarden Research Team
Curcumin, the most active compound of turmeric, is one of the most powerful botanicals in the world today.
Curcumin offers a wide spectrum of benefits to the body because of its antioxidant and anti-inﬂammatory properties. It helps to both prevent and fight a wide range of serious inflammatory diseases such as arthritis, metabolic diseases, cardiovascular disease and cancer — through a variety of mechanisms. These include powerful anti-inflammatory, antioxidant, chemo-preventive (cancer-preventive), and antineoplastic (cancer-fighting) properties.
But despite its rich antioxidant properties that make it a potent agent to fight these serious, chronic conditions and its impressive array of beneficial bio-activities, the poor bio-availability of curcumin in the human body severely limits its application to these diseases.
One of the most important activities of curcumin in the human body is its ability to inhibit activation of the transcription factor, nuclear factor-kappa B (NF-kB), a potent inducer of chronic inflammation. NF-kB is a protein that turns on inflammation by activating genes involved in the production of inflammatory compounds. As NF-kB activation is the reason behind all stages of carcinogenesis, this transcription factor is a potential target in cancer chemoprevention and is the subject of intensive research.
Enhanced bio-availability with BCM-95™:
Despite its many benefits, the effectiveness of oral supplementation with curcumin has been limited by its poor absorption into the bloodstream through the digestive tract.
This is where BCM-95™, a bio-available form of curcumin that provides even greater pharmaceutical potencies to maximize curcumin’s efficacy, comes in. BCM-95™, a 100 percent standardized extract of turmeric, is produced with a unique and patented process that delivers a superior-absorbing curcumin formulation that is seven to 10 times more bio-available than conventional curcumin extracts!
A recent analysis of curcumin products with enhanced absorption shows that blood levels of BCM-95™ are not only much higher than other forms of curcumin, but that they also remain in the bloodstream for 8 to 12 hours.
BCM-95 amplifies and potentiates curcumin’s effectiveness, explains Dr. Ajay Goel, Ph.D. of the Gastrointestinal Cancer Research lab at Baylor University. “Abundant data point to the pain-relieving and anti-inflammatory efficacy of curcumin and these benefits are essentially drawn from its ability to suppress and inhibit the activities of two major pro-inflammatory targets within our cells: NF-kB and COX-2, an enzyme that causes inflammation."
Dr. Goel’s research group demonstrated that curcumin acts as a specific COX-2 inhibitor, and plays an important role in not only erasing pain, but also has the capability to prevent chronic diseases that occur due to inflammation. Studies show the enhanced effectiveness of BCM-95 on various ailments from joint disease and diabetes, to gastric conditions, cardiovascular disease and depression.
Benny M. Antony. B. Bio-availability of Biocurcumax (BCM-95). Spice India. September, 2006: 11-15
Merina B. Iyer VS et al. A pilot cross-over study to evaluate human oral bio-availability of BCM-95CG (Biocurcumax), a novel bio-enhanced preparation of curcumin, Ind J Pharm Sci. 2008; 70 (4): 445-449
Poster Presentation. Oral Bio-availability of BCM-95 Curcumin in Dogs. 2009 ACVIM Forum/Canadian VMA Convention: June 3-6, 2009; Montreal, Quebec, Canada
Curcumin, The 21st Centure Cure, Jan McBarron. M.D, N.D.
Curegarden represents a dream. A dream of sharing a happier, healthier body and quality of life with the use of nature's best ingredients. Botanics, when extracted for their bioactive compounds, offer a most effective approach to improving well-being and quality of life. It is based on the belief that botanicals of the highest quality would have a positive effect — without any negative side effects — on people's health. Over the years,we have seen and experienced personally the wonderful benefits of these high quality botanical products and are delighted to share them with others.
Arjuna Natural Extracts Ltd is India’s leading manufacturer and exporter of standardized botanical extracts for pharmaceutical and nutraceutical industries for over two decades. With customers in around 40 countries, the company has close to 50 patents to its credit of which majority are commercialized globally. The company has R&D tie ups with international universities from Australia, US and Japan. The highly advanced R&D unit at Arjuna is a complete research facility for phytochemistry, pharmacokinetics, formulation and development, pre-clinical and clinical studies.
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